IMO D.
Genetically modified seeds,
with no requirement of costly fertilizer or with expensive agriculture, help farmers grow crops in a cost effective manner.
(A) with no requirement of costly fertilizer
or with expensive agriculture, help - Meaning clarity error; as mentioned 'cost effective manner' in non underlined part of the sentence, '...... or with expensive agriculture' contrasts the information, ultimately changing the intended meaning of the sentence.
(B) with no requirements of costly fertilizer or expensive agriculture,
helps - SVA error; GMS (plural) ,....., helps (singular)
(C) having no requirement of costly fertilizer or with expensive agriculture,
helps - SVA error; GMS (plural) ,....., helps (singular)
(D) without the requirement of costly fertilizer or expensive agriculture, help - No error
(E) without the requirement of costly fertilizer or
no expensive agriculture, help - Redundancy error which alters the meaning of the sentence.