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In response to viral infection, the immune systems of mice typically

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Senior Manager
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In response to viral infection, the immune systems of mice typically [#permalink]

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New post 16 May 2005, 10:10
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A
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E

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Official Guide for GMAT Verbal Review, 2nd Edition

Practice Question
Question No.: 62
Page: 141

In response to viral infection, the immune systems of mice typically produce antibodies that destroy the virus by binding to proteins on its surface. Mice infected with a herpesvirus generally develop keratitis, a degenerative disease affecting part of the eye. Since proteins on the surface of cells in this part of the eye closely resemble those on the herpesvirus surface, scientists hypothesize that these cases of keratitis are caused by antibodies to herpesvirus.

Which of the following, if true, gives the greatest additional support to the scientist's hypothesis?


(A) Other types of virus have surface proteins that closely resemble proteins found in various organs of mice.

(B) There are mice that are unable to form antibodies in response to herpes infections, and these mice contract herpes at roughly the same rate as other mice.

(C) Mice that are infected with a herpesvirus but do not develop keratitis produce as many antibodies as infected mice that do develop keratitis.

(D) There are mice that are unable to form antibodies in response to herpes infections, and these mice survive these infections without ever developing keratitis.

(E) Mice that have never been infected with a herpesvirus can sometimes develop keratitis.

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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 16 May 2005, 10:21
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I pick D. D says if the mice forms antibodies, it will have keratitis.
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 17 May 2005, 00:27
I too go with D as that is the only option that mentions that without antibodies keratitis is not formed.
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 17 May 2005, 02:15
(D). Pretty tough one to relate all the elements.
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 06 Nov 2005, 12:54
In response to viral infection, the immune systems of mice typically produce antibodies that destroy the virus by binding to proteins on its surface. Mice infected with a herpesvirus generally develop keratitis, a degenerative disease affecting part of the eye. Since proteins on the surface of cells in this part of the eye closely resemble those on the herpesvirus surface, scientists hypothesize that these cases of keratitis are caused by antibodies to herpesvirus.

Which of the following, if true, gives the greatest additional support to the scientist's hypothesis?

A. Other types of virus have surface proteins that closely resemble proteins found in various organs of mice.
B. There are mice that are unable to form antibodies in response to herpes infections, and these mice contract herpes at roughly the same rate as other mice.
C. Mice that are infected with a herpesvirus but do not develop keratitis produce as many antibodies as infected mice that do develop keratitis.
D. There are mice that are unable to form antibodies in response to herpes infections, and these mice survive these infections without ever developing keratitis.
E. Mice that have never been infected with a herpesvirus can sometimes develop keratitis.
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 06 Nov 2005, 22:55
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Antibodies kill both VIRUS and EYE.

No antibodies, no eye damage.

D. There are mice that are unable to form antibodies in response to herpes infections, and these mice survive these infections without ever developing keratitis.
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 07 Nov 2005, 05:47
yup D is the OA.

I was really stuck between D and E.
how did you guyd eliminate E.
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 24 Nov 2005, 01:58
In response to viral infection, the immune systems of mice typically produce antibodies that destroy the virus by binding to proteins on its surface. Mice infected with a herpesvirus generally develop keratitis, a degenerative disease affecting part of the eye. Since proteins on the surface of cells in this part of the eye closely resemble those on the herpesvirus surface, scientists hypothesize that these cases of keratitis are caused by antibodies to herpesvirus.

Which of the following, if true, gives the greatest additional support to the scientists’ hypothesis?

A. Other types of virus have surface proteins that closely resemble proteins found in various organs of mice.
B. There are mice that are unable to form antibodies in response to herpes infections, and these mice contract herpes at roughly the same rate as other mice.
C. Mice that are infected with a herpesvirus but do not develop keratitis produce as many antibodies as infected mice that do develop keratitis.
D. There are mice that are unable to form antibodies in response to herpes infections, and these mice survive these infections without ever developing keratitis.
E. Mice that have never been infected with a herpesvirus can sometimes develop keratitis.
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 24 Nov 2005, 02:56
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It should be D

conlclusion: these cases of keratitis are caused by antibodies to herpesvirus.

Premise1: Mice infected with a herpesvirus generally develop keratitis

Premise2: the immune systems of mice typically produce antibodies that destroy the virus by binding to proteins on its surface.

Premise3:proteins on the surface of cells in this part of the eye closely resemble those on the herpesvirus surface.

we need an evidence to strengthen the conclusion.
the evidence need to show that if a mouse cannot produce antibodies in respose to herpesvirus but did not develop keratitis, the conclusion will be further strengthen.

so D is the right choice.
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 24 Nov 2005, 09:34
D as well. :)
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 20 Jun 2006, 09:53
not clear about the last line " caused by antibodies to herpes virus"

I think answer is E

Scientists hypothosize that anti-bodies cause this disease in which they attach to the the protein on the surface of this virus

Also, the protein is similar to that on the eye ... so the antibodies if produced can attach itself to the protein on the eye and cause the disease too.
Option E states this
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 20 Jun 2006, 09:58
Clearly D

E is out because there are may be other factors that cause the deasease, not necessarily antibodies. So it doesn't prove or refute anything.
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 20 Jun 2006, 10:02
option D states that there are no antibodies but the mice survive the infection ???

this makes the antibodies redundant ... mice cannot survive the infection without antibodies
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 20 Jun 2006, 10:13
foolz_rulz wrote:
option D states that there are no antibodies but the mice survive the infection ???

this makes the antibodies redundant ... mice cannot survive the infection without antibodies


See my additions to the previous post.

As to your arguments, there are plenty of deseases that humans survive for years without developing antibodies. With reduced immunity, one doesn't develop enough antibodies even to the most common deseases. However, taking antibiotics, one can survive for years.

Now to the question, we are told nothing about how those mice actually survived the desease. May be they were given antibiotics or other drugs to suppress the desease.
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 20 Jun 2006, 10:49
Will go with D.

The hypothesis is that the keratitis are formed by the antibodies for the herpes virus.
To support this hypothesis we have to show that mice that dont produce the antibodies done contract heratitis.
THis is stated in D
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 20 Jun 2006, 10:59
D. There are mice that are unable to form antibodies in response to herpes infections, and these mice survive these infections without ever developing keratitis.
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 21 Jun 2006, 05:43
OA is D :)
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 21 Jun 2006, 08:26
Phew! (D) supports the scientists claim.

Tip, on "which of the following" CRs, always start with E and work up.

2:16
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 02 Sep 2006, 22:03
In response to viral infection, the immune systems of mice typically produce antibodies that destroy the virus by binding to proteins on its surface. Mice infected with a herpesvirus generally develop keratitis, a degenerative disease affecting part of the eye. Since proteins on the surface of cells in this part of the eye closely resemble those on the herpesvirus surface, scientists hypothesize that these cases of keratitis are caused by antibodies to herpesvirus.

Which of the following, if true, gives the greatest additional support to the scientists’ hypothesis?

A. Other types of virus have surface proteins that closely resemble proteins found in various organs of mice.
B. There are mice that are unable to form antibodies in response to herpes infections, and these mice contract herpes at roughly the same rate as other mice.
C. Mice that are infected with a herpesvirus but do not develop keratitis produce as many antibodies as infected mice that do develop keratitis.
D. There are mice that are unable to form antibodies in response to herpes infections, and these mice survive these infections without ever developing keratitis.
E. Mice that have never been infected with a herpesvirus can sometimes develop keratitis.
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Re: In response to viral infection, the immune systems of mice typically [#permalink]

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New post 03 Sep 2006, 00:26
D

If mice can not produce antibodies in respose to herpesvirus then they can't develop keratitis. Hence the only cause of keratitis is the antibodies developed in response to herpesvirus.
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Re: In response to viral infection, the immune systems of mice typically   [#permalink] 03 Sep 2006, 00:26

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