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In response to viral infection, the immune systems of mice typically

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In response to viral infection, the immune systems of mice typically  [#permalink]

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New post 20 Jul 2018, 07:45
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A
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C
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GMAT® Official Guide 2019

Practice Question
Question No.: CR02830

In response to viral infection, the immune systems of mice typically produce antibodies that destroy the virus by binding to proteins on its surface. Mice infected with the herpesvirus generally develop keratitis, a degenerative disease affecting part of the eye. Since proteins on the surface of cells in this part of the eye closely resemble those on the herpesvirus surface, scientists hypothesize that these cases of keratitis are caused by antibodies to the herpesvirus.

Which of the following, if true, most helps to support the scientists’ reasoning?

(A) Other types of virus have surface proteins that closely resemble proteins found in various organs of mice.

(B) Mice that are infected with the herpesvirus but do not develop keratitis produce as many antibodies as infected mice that do develop keratitis.

(C) Mice infected with a new strain of the herpesvirus that has different surface proteins did not develop keratitis.

(D) Mice that have never been infected with the herpesvirus can sometimes develop keratitis.

(E) There are mice that are unable to form antibodies in response to herpes infections, and these mice contract herpes at roughly the same rate as other mice.

Similar Question : LINK

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Re: In response to viral infection, the immune systems of mice typically  [#permalink]

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New post 20 Jul 2018, 11:59
hazelnut wrote:
GMAT® Official Guide 2018

Practice Question
Question No.: CR02830

In response to viral infection, the immune systems of mice typically produce antibodies that destroy the virus by binding to proteins on its surface. Mice infected with the herpesvirus generally develop keratitis, a degenerative disease affecting part of the eye. Since proteins on the surface of cells in this part of the eye closely resemble those on the herpesvirus surface, scientists hypothesize that these cases of keratitis are caused by antibodies to the herpesvirus.

Which of the following, if true, most helps to support the scientists’ reasoning?

(A) Other types of virus have surface proteins that closely resemble proteins found in various organs of mice.

(B) Mice that are infected with the herpesvirus but do not develop keratitis produce as many antibodies as infected mice that do develop keratitis.

(C) Mice infected with a new strain of the herpesvirus that has different surface proteins did not develop keratitis.

(D) Mice that have never been infected with the herpesvirus can sometimes develop keratitis.

(E) There are mice that are unable to form antibodies in response to herpes infections, and these mice contract herpes at roughly the same rate as other mice.

Similar Question : LINK


In my opinion the answer should be C as this answer choice picks up on the similarities between Herpes Virus and anti bodies.
Hence, if the different strain of the Virus has different cells, the respective antibodies, given they closely resemble the cell structure of the original Virus, would look different than before and thus not cause Keratitis.

(My explantion is by no means SC sufficient :) )
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In response to viral infection, the immune systems of mice typically  [#permalink]

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New post 29 Jul 2018, 04:41
premise:
1. In response to viral infection, the immune systems of mice typically produce antibodies that destroy the virus by binding to proteins on its(the virus) surface.This is a general responce of a mice in case of a viral infection.
2. Mice infected with the herpesvirus generally develop keratitis, a degenerative disease affecting part of the eye.
3. Since proteins on the surface of cells in this part of the eye closely resemble those on the herpesvirus surface, scientists hypothesize that these cases of keratitis are caused by antibodies to the herpesvirus.
----- Most probable reasoning of scientists to think all this could be that cells react to infection on the basis of surface. as two have close resemblance. it considered this part as virus and coated it with proteins.


Which of the following, if true, most helps to support the scientists’ reasoning?

(C) Mice infected with a new strain of the herpesvirus that has different surface proteins did not develop keratitis. --- this seems to be the correct answer. as keratitis devlopes on the basis of surfacr of virus. if this given virus has different surface, body cell's find a difference in eye cell and this new virus and so no keratitis will be developed.
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Re: In response to viral infection, the immune systems of mice typically  [#permalink]

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New post 29 Jul 2018, 18:04
keratitis are caused by antibodies to the herpesvirus
Reason:
proteins on the surface of cells in this part of the eye closely resemble those on the herpesvirus surface

Now, if surface of cell doesn't resemble with surface of herpesvirus, does Keratitis happen.
If not, it's weakening.

C is close my thinking

C looks like an answer.
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Re: In response to viral infection, the immune systems of mice typically  [#permalink]

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New post 03 Aug 2018, 16:07
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The key to CR questions is to really understand what's going on in the argument.

I recommend boiling down the argument to a couple of sentences using YOUR own words.
Mice with a certain virus ALSO develop a particular degenerative eye disease. Why? It appears that the antibodies that target the virus (by attaching to its protein) also attack cells in the eye. So the antibodies mistake the proteins on the cells of the eye for those on the virus.

Conclusion: The antibodies are responsible for causing the degenerative eye disease (by using the aforementioned mechanism).

In casual statements one way to strengthen the argument is to remove the cause. If the effect is also absent, then you have a strengthener.
Choice (C) accomplishes this task. When you remove the suspected cause (the proteins similar to those on the cells of the eye to which antibodies attach), then the effect (Keratitis) is no longer there. In other words, the antibodies are no longer targeting those particular types of proteins similar in both the original herpervirus and the cells of the eye.
Re: In response to viral infection, the immune systems of mice typically &nbs [#permalink] 03 Aug 2018, 16:07
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