I agree with Brent -- it's not a realistic problem, but we can actually get away with considering just two cases. We have 8 different letters. So if we use each letter once, we'll have 8 choices for the first letter, 7 for the second, and so on, for 8*7*6*5 = 1680 words we can make using four different letters. Most of the remaining words will look like EIEM, where we use exactly one letter twice. We have 2 choices for that letter (only T and E are repeated), and then we have 4C2 = 6 choices for which two positions those letters will occupy in the word (choosing from the 1st, 2nd, 3rd and 4th letters in the word). So we have 2*6 = 12 ways to position two repeated letters in a word, and then we'll have 7 choices for the first empty slot in the word, and 6 for the second, for 12*7*6 = 504 possible words that use one letter twice and two letters once.
We're already well past 2000 possible words, leaving D as the only plausible answer, and we don't need to count the two remaining cases (where we use both the T and E twice, which gives only 6 possibilities, and where we use the E all three times, and some other letter once, which turns out to give only 28 possibilities).
But I think it's better to practice questions more similar to what will show up on the actual test.