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tchanou
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Thanks ChrisLele for the accurate explanation.
Actually my choice was D, but now I can notice that it is a bit changing the meaning of the original sentence by ignoring the subject of the passive voice (earlier without any signs of the disease shown then).

But tell me, if answer D was instead

D- "earlier without showing any signs of the disease then",

It would be a better answer choice than answer A because it not only eliminates the pronoun THEY, but also clearly tells that the rats are the ones showing the signs of the disease.

Do you agree with me?
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ChrisLele, thank you for the detailed explanation. I was down with A and E but chose E as I thought they may refer to any of the two, but now I see what is the logical referent. However, what is wrong with E, it refers to disease and them will refer to by logic again to rats? Please explain in case I am missing on something.
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@pavanpuneet:

Answer choice (E) uses the passive construction, '...were seen in them...', and is therefore less concise than the original answer.

Hope that helps :)
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Should I in that case interpret that it is because of the passive construction that the answer choice is rejected and not because the pronoun use? or in other words if GMAT allowed two options as correct answers E would be the second option? Please confirm.
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Exactly: the answer choice is incorrect because the passive construction is used, not because of the pronoun.
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I would chose E.
Basic Question: Why few options has then at the end of A, B and D? Does is holds any meaning or rule in grammar?
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it has to be E : earlier, even though no signs of it were seen in them at that time
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isn't 'they' ambiguous? can't it refer to rats or scientists?
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I wouldn’t entertain any doubts about the pronoun in the close - running choices A and E. After all, the disease is all about the rats and not about the scientists. In E also, there is no doubt about ‘it and them ‘(not they as somebody has pointed out; there is no ‘they’ in that choice at all) And such touch and go reference is the basis of the modern day pronoun - based questions. If one cannot logically see through the reference, it is going to be difficult
But the only difference I see between A and E is that both arms of the sentences are in active voice in A, while they are in active- passive mode in E. But I wouldn’t know whether GMAT will test a question on such trivial grounds alone
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Who can explain how to make sure that 'they' in the second sentence after comma refers to rats and not the scientists themselves.

Also official explanation for answer choice E mentions usage of pronouns 'it' and 'they' introduces ambiguity. Really?
I thought 'it' clearly refers to the disease without any ambiguity and them in this case should be rats (by commonsense). Can somebody please clarify in details?
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Hi experts,
What is the difference between (A) and (D)?

IMHO,(D) tells us that the rats died and that they showed no signs of the disease.
This meaning is quite the same as what (A) says.

Please share your thoughts.
Thanks
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sleepynut
Hi experts,
What is the difference between (A) and (D)?

IMHO,(D) tells us that the rats died and that they showed no signs of the disease.
This meaning is quite the same as what (A) says.

Please share your thoughts.
Thanks

In D it is not clear who showed the signs. There is no grammatical error in D - A is better because it has more clarity than D.
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Can someone explain the usage of "had begun" and "had shown" in option A. How are we differentiating the timeline using two past perfect tenses?
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smlprkh
Can someone explain the usage of "had begun" and "had shown" in option A. How are we differentiating the timeline using two past perfect tenses?
There is a verb in the simple past tense (noted) in the non-underlined portion at the beginning of the sentence, and the author of the sentence is setting the verbs you mentioned (had begun and had shown) up as being in the past relative to the noted.
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ChrisLele
@pavanpuneet:

Answer choice (E) uses the passive construction, '...were seen in them...', and is therefore less concise than the original answer.

Hope that helps :)
ChrisLele hello expert, I picked E cuz in A the second part also uses past perfect tense, but GMAT usually uses simple past+past perfect rather than 2 past perfect. Can you throw some light on this? Thanks
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I am confused between E and A.
I chose E because in A, I assumed a meaning ambiguity. In A, it is as if the Rats had shown the signs themselves. The ambiguity is cleared in option E as it is in passive voice.

I am not able to find any grammatical error in A or E. If anyone can help me clarify my doubt.

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