Tumours are group of abnormal cells that form lumps of growths and these may be benign or malignant; the most effective way to cure a benign Tumour is to immediately remove it before it spreads and becomes irremovable.

A. to immediately remove it before it spreads and becomes irremovable.
B. if it is immediately removed before it spread to become irremovable.
C. to be removed immediately before the Tumour spreads and becomes irremovable.
D. that it is immediately removed before it spreads to become irremovable.
E. to have it immediately removed before it spreads and becomes irremovable.

Source:- expertsglobal

A convey wrong meaning it means that a person has to remove tumour on its own whereas E convey that a person has to removed it by someone immediately Hope i was able to clarify your question.

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I actually disagree with your explanation. The second part of the sentence states "the most effective way to cure a benign Tumour [...]". Someone can cure a tumor from another person, therefore A doesn't imply that a person has to cure the tumor by removing it himselve.

In my opinion, the mistake in A is that the verb is splitted "to immediately remove". "To" and the infinitive shouldn't be seperated by an adverb or any other word. If this logic is correct, changing the sentence to "to remove it immediately" would fix answer A and make it valid.

Because of the mistake I explained, E is preferrable over A.

Let me know what you think about my reasoning [/quote]
basically look at this phase "Tumour is to immediately remove" this seems like you have something that causes problem and you have to simply remove it but in E "to have it immediately removed" this means to remove it by someone else. If you read meaning you will realize that even the source is saying thing after your explanation i saw this information from the source.